Brewers vs. Mariners prediction, odds, props, best bets: Free 2025 MLB picks for Tuesday, July 22

The Milwaukee Brewers are on the road to square off against the Seattle Mariners on Tuesday evening. On Monday, Milwaukee shut out the Mariners en route to a 6-0 victory. The Brewers have now won four straight games. On the flip side, Seattle has dropped two straight games after winning the first two matchups out of All-Star break. NL Rookie of the Year candidate Jacob Misiorowski (4-1, 2.81 ERA) gets the start for the Brewers. Logan Gilbert (2-3, 3.39 ERA) gets the ball for the home team.

First pitch from T-Mobile Park in Seattle is set for 9:40 p.m. ET. Seattle is a -126 favorite (risk $126 to win $100) in the latest Brewers vs. Mariners odds from DraftKings Sportsbook, while Milwaukee is a +104 underdog (risk $100 to win $104). The over/under for total runs scored is 7. Seattle’s Cal Raleigh, who leads the majors with 38 home runs, is +245 to hit a homer, while Misiorowski is +120 to throw 7+ strikeouts. Before making any Brewers vs. Mariners picks, be sure to see the MLB betting predictions from SportsLine’s proven model. Bet on Brewers vs. Mariners and every other MLB game at DraftKings, where you can get $150 in bonus bets instantly with the latest DraftKings promo code:

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 17 of the 2025 MLB season 46-43 on top-rated MLB picks. It has excelled making home run prop picks this season, returning more than 40 units of profit. Anybody following at sportsbooks and on betting apps could have seen strong returns, especially when paired with the latest BetMGM promo code and FanDuel promo code, just to name a few. At BetMGM, new users can get up to $1,500 back in bonus bets if their first bet loses. 

Here are the model’s three best bets for Brewers vs. Mariners on Tuesday:

• J.P. Crawford Over 0.5 hits (-160)
• Jackson Chourio Seager Total Bases Over 1.5 (+140)
• Jacob Lopez Over 5.5 strikeouts (+110)

J.P. Crawford Over 0.5 hits (-160)

Crawford leads the team in batting average (.285), OBP (.384) and hits (103). He’s finished with over 0.5 hits in 13 of his last 15 outings. On Sunday against the Astros, Crawford went 2-of-5 with two singles. The model is projecting him to finish with 0.8 hits in Tuesday’s contest against Milwaukee. 

Jackson Chourio Total Bases Over 1.5 (+140)

Chourio rolls into this affair with a .267 batting average, 16 dingers, and 64 RBI. He’s also leading the club in hits (112). He’s gone over 1.5 total bases in four of his last six games. In last night’s game against Seattle, the 21-year-old went 2-of-4. The SportsLine model projects him to log 1.7 total bases. 

Logan Gilbert Over 6.5 strikeouts (-145)

Gilbert heads on the mound with 3.39 ERA along with 88 strikeouts on the season. The 28-year-old has gone over 6.5 strikeouts in seven of his last 10 games. In his last start against the Tigers, Gilbert tossed 9 Ks in 5.1 innings. In two career starts against the Brewers, Gilbert has finished with at least seven strikeouts.

Want more MLB picks for Tuesday?

You’ve seen the model’s MLB picks for Brewers vs. Mariners on Tuesday. Now, get more MLB picks from No. 1 expert Bruce Marshall, who is up nearly 17 units on his last 104 MLB picks.