Wednesday’s MLB schedule is packed with several matchups with playoff implications, and new users wanting to get in on the action can use the latest FanDuel promo code, good for $300 in bonus bets if your first wager of $5 or more wins. You can also use the latest FanDuel promo code to raise your bankroll for NFL Week 2, which kicks off on Thursday when the Washington Commanders visit the Green Bay Packers. On Wednesday, the Toronto Blue Jays and Houston Astros play in a battle between two first-place teams at 7:07 p.m. ET. The Blue Jays are -130 money-line favorites in today’s MLB odds, but SportsLine’s computer model is backing the Over 8.5 runs in Astros vs. Blue Jays. Toronto is expected to start right-hander Jose Berrios (9-5, 4.02 ERA), while Houston will counter with Jason Alexander (4-1, 4.68 ERA).
The model is also backing the Over (8) in Tigers vs. Yankees, along with the Dodgers (-330) on the money-line on Wednesday. Before locking in your MLB picks on your favorite betting sites like FanDuel, be sure to check out the top MLB betting picks from SportsLine’s proven computer model. The latest FanDuel promo code, which offers new users $300 in bonus bets if your first wager of $5 or more wins. Claim that offer here.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 25 of the 2025 MLB season a profitable 34-25 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning more than 60 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.
Best MLB picks:
- Blue Jays moneyline vs. Astros (-130)
- Over 8 total runs in Tigers vs. Yankees (-120)
- Dodgers moneyline vs. Rockies (-330)
Combining the model’s three picks into an MLB parlay at FanDuel would result in a payout of +319 (risk $100 to win $319). Bet it at FanDuel here:
Blue Jays moneyline vs. Astros (-130)
The Blue Jays enter this game with the best record in the AL, winning four of their last six games. Toronto is 44-30 on the season as the favorite and 48-34 following a win. Right fielder George Springer is seventh in the league in batting average (.300) and third in OPS (.943) while leading the team in home runs (28). Meanwhile, Houston has dropped four of their last five games. The model has the Blue Jays winning this game in 59% of simulations.
Over 8 total runs in Tigers vs. Yankees
Entering this matchup, the Yankees led the majors in home runs (245), with the Tigers being tied for the ninth spot (181). New York also has the highest scoring offense in the MLB with 5.2 runs per game. Detroit logs 4.8 runs per game, which is good for eighth in the majors. The Over has cashed in three of the last six games for the Yankees. Meanwhile, the Over has hit in three of the last four games with Detroit. The model has these teams combining for 9.7 total runs in Tuesday’s contest and goes Over in 59% of simulations.
Dodgers moneyline vs. Rockies (-330)
Los Angeles is on a three-game winning streak and is on the verge of sweeping the Rockies in this NL West contest. The Dodgers are 8-2 in the last 10 games against the Rockies. Los Angeles also has a 28-13 record in division games this season. In addition, they own a 47-26 record as the home team. Shohei Ohtani has 48 home runs and 91 RBI in the lineup for Los Angeles. Colorado also has a 39-104 record as the underdog. The model has the Dodgers winning outright in 71% of the time to provide value on this line at FanDuel.
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