Pelicans vs. Pacers prediction, odds, spread start time: 2026 NBA picks for Friday, Jan. 16

The New Orleans Pelicans will look to sweep the two-game season series with the Indiana Pacers when they meet in NBA action on Friday night. New Orleans is coming off a 116-113 win over Brooklyn on Wednesday, while Indiana dropped a 115-101 decision to Toronto that same night. The Pelicans (10-33), who are fifth in the Southwest Division, are 3-15 on the road this season. The Pacers (9-32), who are fifth in the Central Division, are 7-16 on their home court. Herbert Jones (ankle) and Jose Alvarado (oblique) will miss the game for New Orleans, while Bennedict Mathurin (thumb) and Isaiah Jackson (concussion) are out for Indiana.

Tioff from Gainbridge Fieldhouse in Indianapolis, is set for 7 p.m. ET. Indiana is a 4-point favorite in the latest Pelicans vs. Pacers odds from DraftKings Sportsbook, while the over/under for total points scored is 241.5. Before making any Pacers vs. Pelicans picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 13 of the 2025-26 NBA season on a sizzling 34-15 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.    

Now, the model has simulated Pelicans vs. Pacers 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Pacers vs. Pelicans:

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How to make Pelicans vs. Pacers picks

SportsLine’s model is going Under on the total (241.5 points). The last New Orleans game went under the total, while Indiana has seen five straight games fail to hit the total. The model is projecting 239 combined points as the Under hits in 55% of simulations. 

It has also generated an against-the-spread pick that hits well over 60% of the time. You can head to SportsLine to see the model’s NBA picks. 

So who wins Pacers vs. Pelicans, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the Pelicans vs. Pacers spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.