Celtics vs. Pistons prediction, odds, spread, time: 2025 NBA picks from proven model

The 2025 NBA season rolls on with a huge Eastern Conference matchup on Monday as the Boston Celtics and Detroit Pistons get the day’s action underway. Detroit leads the East with a 20-5 record, while Boston is in third place and five games back at 15-10. The teams have split their two head-to-head matchups thus far and they have matching 14-11 records against the spread this season.

Tipoff from TD Garden in Boston is at 7 p.m. ET. Boston is a 1.5-point favorite at home, while the over/under is 230.5 in the latest Celtics vs. Pistons odds. Before making any Celtics vs. Pistons picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

New users can also target the latest Underdog promo code, good for $75 in bonus entries when you play $5 with the promo code CBSSPORTS2 in select states.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 8 of the 2025-26 NBA season on a sizzling 29-14 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Celtics vs. Pistons 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Pistons vs. Celtics

New users can check out the latest bet365 bonus code to get $150 in bonus bets after placing a $5 bet:

How to make Celtics vs. Pistons picks

After 10,000 simulations of Pistons vs. Celtics, SportsLine’s model is going Over on the total (230.5 points). Hitting the Over has been a recent trend for both teams. Three straight Detroit games have cleared the total, while four of the last five have done the same for Boston. 

The model is projecting nine players to hit double-digit scoring in this one with Jaylen Brown (27.1 points) leading the way for Boston in the simulations and Cade Cunningham (23.9 points) pacing Detroit. The model is projecting 239 combined points as the Over hits more than 60% of the time. 

The model also says one side of the spread hits nearly 70% of the time. You can head to SportsLine to see the model’s NBA picks. 

So who wins Celtics vs. Pistons, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.