The Los Angeles Dodgers and the Minnesota Twins wrap up their intraleague series on Wednesday. The first two games were split, with the Twins are coming off a 10-7 victory over the Dodgers last night. Los Angeles is now 1-4 post-All-Star break, while the Twins have gone 2-3. Chris Paddack (3-9, 5.14 ERA) takes the hill for the Twins. Tyler Glasnow (1-1, 3.10 ERA) goes on the mound for Los Angeles.
First pitch from Dodger Stadium in Los Angeles is set for 4:10 p.m. ET. Los Angeles is a -243 favorite (risk $243 to win $100) in the latest Twins vs. Dodgers odds from DraftKings Sportsbook, while Minnesota is a +195 underdog (risk $100 to win $195). The over/under for total runs scored is 8.5. Before making any Twins vs. Dodgers picks, be sure to see the MLB betting predictions from SportsLine’s proven model. Bet on Twins vs. Dodgers and every other MLB game at DraftKings, where you can get $150 in bonus bets instantly with the latest DraftKings promo code:
The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 17 of the 2025 MLB season 46-43 on top-rated MLB picks. It has excelled making home run prop picks this season, returning more than 40 units of profit. Anybody following at sportsbooks and on betting apps could have seen strong returns, especially when paired with the latest BetMGM promo code and FanDuel promo code, just to name a few. At BetMGM, new users can get up to $1,500 back in bonus bets if their first bet loses.
Here are the model’s three best bets for Twins vs. Dodgers on Wednesday:
- Shohei Ohtani Under 1.5 hits (-225)
- Byron Buxton 2+ Total Bases (+110)
- Chris Paddack Under 3.5 strikeouts (+100)
Shohei Ohtani Under 1.5 hits (-225)
Ohtani is one of the top power hitters in the league, ranking second in the MLB in home runs (36) and he is tied for 12th in RBI (69). Despite that, he hasn’t consistently put together multi-hit games. He’s gone under 1.5 hits in 13 of his last 15 games. The model is projecting him to record 0.9 hits in this game. Last night, Ohtani was 1-of-5 with a two-run homer at the dish.
Byron Buxton 2+ Total Bases (+110)
Buxton is currently leading the Twins across the board, in batting average (.290), home runs (23), RBI (58) and hits (92). He goes into this matchup with 2+ total bases in seven of his last 10 games. SportsLine’s model predicts he’ll get 2.4 total bases.
Chris Paddack Under 3.5 strikeouts (+100)
Paddack has 75 strikeouts on the campaign but hasn’t racked up consistent K’s during his outings. The under has hit in 9 of his last 15 outings when the strikeout line is at 3.5. Paddack has tossed less than four K’s in two of his last four games against Los Angeles as well.
Want more MLB picks for Wednesday?
You’ve seen the model’s MLB picks for Twins vs. Dodgers on Wednesday. Now, get more MLB picks from No. 1 expert Bruce Marshall, who is up more than 13 units on his last 107 MLB picks.