Check out all of our starting pitcher rankings and other lineup selection tools here to help you make smart fantasy baseball lineup decisions. All fantasy advice is geared toward ESPN 10-team leagues with standard scoring.
Note: All information is accurate as of the time of publication. For updates, as well as any breaking news that might impact today’s MLB slate, be sure to check out the latest fantasy baseball buzz.
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ESPN’s 2026 Draft Guide | Betting notes for Wednesday
Pitchers to stream on Wednesday
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Detroit Tigers starter Jack Flaherty is slow out of the gate, but he showed signs of returning to form in his last outing, and his velocity is in line with his usual levels. His walks are uncharacteristically high. They’re up across the league, but Flaherty’s 16.7% walk rate is especially bloated. Flaherty’s opponent at Comerica Park on Wednesday is the Kansas City Royals, whose lineup exhibits average patience but sports the seventh-lowest wOBA in the league.
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The Houston Astros have a problem with Hunter Brown, Tatsuya Imai and Cristian Javier all on the IL. They’re hoping Spencer Arrighetti can give their rotation a much-needed boost against the Colorado Rockies at Daikin Park. The promotion from Triple-A Sugar Land wasn’t solely out of desperation, as Arrighetti posted a 1.26 ERA and 0.78 WHIP and 20 strikeouts over 14 1/3 innings. He’ll face a below-average offense with the second-highest strikeout rate in MLB on Wednesday.
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It has been an uneven start to the season for Slade Cecconi, as his second start was a gem, but it was sandwiched between two subpar efforts. However, his underlying metrics are encouraging, and Wednesday brings a favorable matchup against a not-so-daunting St. Louis Cardinals lineup at pitcher-friendly Busch Stadium.
Pitchers to avoid on Wednesday
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Normally, the bullet point is used for heavily-rostered starting pitchers with a non-favorable matchup. Wednesday is a rare instance of warning against what feels like a trap game for Luis Gil when the New York Yankees host the Los Angeles Angels. It’s not captured by the rankings because they (correctly) rely more on history than short-term trends, so call this a gut call. Gil struggles with control, but he misses plenty of bats and generally keeps the ball in the yard. In his 2026 debut last week, Gil walked three, had a hit batsman and a wild pitch in just four innings. His debut was not delayed by injury, but rather because the Yankees didn’t need a fifth starter for a couple of weeks. In his sole appearance with Triple-A Scranton/Wilkes-Barre, Gil walked four in 4 2/3 innings. The Angels at home should be a favorable matchup, but they are the fourth-most patient offense and have the fifth-highest home run rate in the majors.
Hitters to stream on Wednesday
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The Cincinnati Reds shuffled their lineup, sending Noelvi Marte to Triple-A Louisville after his slow start. Rece Hinds will get a look in right field while Marte tries to get back on track. It’s unclear whether Hinds will platoon with Will Benson, but with lefty Tyler Mahle on the mound for the San Francisco Giants, Hinds will be in the lineup, though likely toward the bottom of the order. Fellow right-handed swingers Matt McLain and Spencer Steer will hit in the upper half of the lineup in what should be a productive effort.