2025 Week 11 College Football Predictions for Every Game

No. 2 Indiana (9-0) at Penn State (3-5), Noon ET

Indiana hasn’t yielded more than 20 points all season. This is simply an exceptional team. Penn State must be respected because of its defensive upside, but an offense that has mustered 3.5 yards per snap without Drew Allar is a problem.

Prediction: Indiana 34, Penn State 17

No. 5 Georgia (7-1) at Mississippi State (5-4), Noon

For the sake of not burying the lede, I’ll take Georgia. I don’t trust Mississippi State’s defense to stop giving up 400-plus yards and 30-some points to SEC opponents. However, an up-and-down UGA defense cannot afford to have a slow day against Blake Shapen. He’s quietly been a very efficient passer in 2025, and MSU only lost to both Tennessee and Texas by seven points at home.

Prediction: Georgia 33, Mississippi State 27

No. 1 Ohio State (8-0) at Purdue (2-7), 1 p.m.

Purdue stuck with Michigan in the Big House last weekend, so the Boilers should have a bit more confidence at home. Also, you won’t find me saying Ohio State—which has allowed 6.9 points per game—will lose to Purdue.

Prediction: Ohio State 41, Purdue 10

The Citadel (4-5) at No. 7 Ole Miss (8-1), 1 p.m.

Clemson defeated The Citadel 51-14 last season, and that 37-point difference was the lower-division program’s closest margin against an FBS opponent since 2020. No fancy analysis necessary here.

Prediction: Ole Miss 56, The Citadel 10

SMU (6-3) at Boston College (1-8), Noon
Prediction: SMU 31, Boston College 20

Colorado (3-6) at West Virginia (3-6), Noon
Prediction: WVU 34, Colorado 24

Temple (5-4) at Army (4-4), Noon
Prediction: Army 28, Temple 23

James Madison (7-1) at Marshall (4-4), Noon
Prediction: JMU 35, Marshall 21

Southern Miss (6-2) at Arkansas State (5-4), Noon
Prediction: Southern Miss 33, Arkansas State 27

Missouri State (5-3) at Liberty (4-4), 1 p.m.
Prediction: Liberty 30, Missouri State 26

Bowling Green (3-6) at Eastern Michigan (2-7), 1 p.m.
Prediction: EMU 24, BGSU 21

UAB (3-5) at Rice (4-5), 2 p.m.
Prediction: UAB 27, Rice 23

Maryland (4-4) at Rutgers (4-5), 2:30 p.m.
Prediction: Rutgers 31, Maryland 29

Charlotte (1-7) at East Carolina (5-3), 3 p.m.
Prediction: ECU 42, Charlotte 17

Tulsa (2-6) at Florida Atlantic (3-5), 3 p.m.
Prediction: FAU 37, Tulsa 31

Jacksonville State (5-3) at UTEP (2-6), 3 p.m.
Prediction: Jax State 27, UTEP 24

Louisiana Tech (5-3) at Delaware (4-4), 3 p.m.
Prediction: Delaware 28, Louisiana Tech 27

Florida International (3-5) at Middle Tennessee (1-7), 3 p.m.
Prediction: MTSU 26, FIU 23