Spurs vs. Pelicans prediction, odds, line: 2025 NBA picks from proven model

Western Conference teams that are missing their biggest star meet in the nightcap on Monday when the San Antonio Spurs travel to take on the New Orleans Pelicans. The Spurs are 15-7 overall, while the Pelicans are 3-21 and have dropped six straight. Victor Wembanyama (calf) remains out for San Antonio, while Stephon Castle (hip) is questionable. Zion Williamson (adductor) is out for New Orleans. Dejounte Murray (Achilles) and Jordan Poole (quad) will also miss this one, with Herbert Jones (calf) listed as questionable. 

Tipoff from the Smoothie King Center is set for 8 p.m. ET. San Antonio is a 9.5-point road favorite in the latest Spurs vs. Pelicans odds, while the over/under is 238.5. Before making Pelicans vs. Spurs picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 7 of the 2025-26 NBA season on a sizzling 29-14 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Spurs vs. Pelicans 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Pelicans vs. Spurs:

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How to make Spurs vs. Pelicans picks

SportsLine’s model has simulated Pelicans vs. Spurs 10,000 times and is leaning Under the total, projecting 231 combined points. 

The model also says one side of the spread hits nearly 60% of the time. You can head to SportsLine to see that pick. 

So who wins Spurs vs. Pelicans, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.